Mediterranean diet may decrease risk of prostate cancer progression
In a study to examine a Mediterranean diet in relation to cancer">prostate cancer progression in men on active surveillance, researchers found that men with localized cancer who reported a baseline dietary pattern that more closely follows the key principles of a Mediterranean-style diet fared better over the course of their disease.
Washington: In a study to examine a Mediterranean diet in relation to prostate cancer progression in men on active surveillance, researchers found that men with localized prostate cancer who reported a baseline dietary pattern that more closely follows the key principles of a Mediterranean-style diet fared better over the course of their disease.
"Men with prostate cancer are motivated to find a way to impact the advancement of their disease and improve their quality of life," said Justin Gregg, M.D., assistant professor of Urology and lead author of the study, published today in Cancer.
"A Mediterranean diet is non-invasive, good for overall health and, as shown by this study, has the potential to effect the progression of their cancer," added Gregg.
After adjusting for factors known to increase risk of cancer getting worse over time, such as age, prostate-specific antigen (PSA) and tumor volume, men with a diet that contained more fruits, vegetables, legumes, cereals and fish had a reduced risk of their prostate cancer growing or advancing to a point where many would consider active treatment. The researchers also examined the effect of diabetes and statin use and found a similar risk reduction in these patient groups.
The study, whose largest number of participants were white, also found that the effect of a Mediterranean diet was more pronounced in African American participants and others who self-identified as non-white.
These findings are significant as the rate of prostate cancer diagnosis is more than 50% higher in African American men, who also have a higher risk of cancer">prostate cancer death and disease progression.
"The Mediterranean diet consistently has been linked to lower risk of cancer, cardiovascular disease and mortality. This study in men with early stage prostate cancer gets us another step closer to providing evidence-based dietary recommendations to optimize outcomes in cancer patients, who along with their families, have many questions in this area," said Carrie Daniel-MacDougall, Ph.D., associate professor of Epidemiology and senior author of the study.
After skin cancer, prostate cancer is the most common cancer in men in the United States. Since most cases are low-risk disease, localized to the prostate and have favorable outcomes, many men do not need immediate treatment and opt for active surveillance by their doctor.
"Our findings suggest that consistently following a diet rich in plant foods, fish and a healthy balance of monounsaturated fats may be beneficial for men diagnosed with early-stage cancer">prostate cancer," Gregg said.
"We are hopeful that these results, paired with additional research and future validation, will encourage patients to adapt a healthy lifestyle," added Gregg. (ANI)